Notes

Site-Selective Electrochemical C-H Cyanation involving Indoles.
Squamous cell (SCC) and basal cell (BCC) skin cancer are common presentations in elderly patients. Skin cancer are often located in sun exposed areas where damage from exposure has occurred. The sun exposed areas are often difficult to close or would require more complex measures to cover. Skin grafts or rotation flaps are commonly employed for coverage. Having tumor free margins is required to anticipate avoiding local recurrence. Mohs techniques examine the surgical margin to ensure that lesions are completely excised. When reliable frozen section is not available for immediate confirmation, permanent section may be used. Excising lesions and implementing radial identification allows margin localization of involved margins for re-excision. Divided into quartets, directed re-excision can be undertaken with minimal disturbance to the healing wound bed. Use of an ECM device (Myriad™, Aroa Biosurgery, Auckland, New Zealand) accelerates healing and leaves a cosmetically acceptable result that affords margin examination and re-excision with minimal disturbance to healing wound. Here we present an evolving technique of excision of common skin cancers utilizing ECM Matrix Graft technology and healing. This technique affords margin identification utilizing permanent section examination. Subsequent margin identification and re-excision if necessary is localized to individual quadrants of the excision site allowing more precise re-excision and not disturbing the grafted wound site. PLX5622 Healing seems accelerated and cosmetic appearance is acceptable to patients.The aim of this review article is to provide an overview of the literature relevant to the peripartal period in swine. As in all other mammals, the farrowing process in pigs is divided into 3 phases (I-III; opening, expulsion, and postnatal stage), during which various essential endocrine and metabolic mechanisms initiate or maintain parturition. These include the hormones progesterone, cortisol, prostaglandin F2α, oxytocin, estradiol, relaxin as well as electrolytes, enzymes, and metabolites such as calcium, magnesium, inorganic phosphate, glucose, creatine kinase, lactate, non-esterified free fatty acids, and β-hydroxybutyrate. Exogenous or endogenous disruptive factors may result in a delay or even stagnation of labor. For example, the form of husbandry may represent a possible exogenous disruptive factor. Endogenous disruptive factors may arise from insufficient storage and/or distribution of the above-mentioned labor-associated parameters. Subsequent dystocia leads to temporary or permanent consequences for maternal reproductive fitness and impairs piglet vitality at the time of birth, possibly resulting in lower survival rates.
The use of low-energy electron irradiation for hatching egg disinfection was compared to formaldehyde fumigation.

To assess the efficacy, eggshells were examined for bacteria before and after disinfection. During incubation, hatching and fattening of 1400 Ross 308 broilers per group candling data, hatching rate, mortality rate and body mass development were recorded to evaluate the impact on health and performance. Additionally, data from the slaughter house and histological evaluation of organ samples were included in the health screening.

Regarding the efficacy, irradiation and formaldehyde significantly reduced the number of bacteria compared to non-disinfected eggs. However, no significant difference was recorded between both treatments. The irradiated group performed better than the reference group concerning the number of infertile eggs, early and late dead embryos and fertile eggs. The performance during fattening was nearly identical in both groups, while mortality differed slightly between the irradiated group and the group treated with formaldehyde. Upon slaughter, there were minor variations concerning the distribution of findings between the groups, but the number of anomalies was not higher than reference values suggest.

In both groups no health problems were observed during rearing and the fattening performance met the targets of the manufacturer Aviagen for the used broiler line Ross 308.

Lower-energy electron irradiation proves to be an efficient and well-tolerated hatching egg disinfection procedure. Further field trials are necessary to establish low-energy electron irradiation as an alternative to formaldehyde fumigation.
Lower-energy electron irradiation proves to be an efficient and well-tolerated hatching egg disinfection procedure. Further field trials are necessary to establish low-energy electron irradiation as an alternative to formaldehyde fumigation.
Protothecal mastitis has emerged and affected the dairy industries globally in last decades; however, little is known about the occurrence of
in Taiwan. The present study identified the
isolated from bovine milk and revealed the algaecide efficacy of 2 disinfectants.

From 2011 to 2014, a total of 176
isolates were obtained from 10 625 milk samples collected from dairy cows in 24 Taiwanese dairy farms. Of these, 149 isolates were identified by biochemical tests and genotype differentiation with a specific PCR protocol. Minimal algaecide concentration (MAC) of chlorhexidine and povidone-iodine were obtained from 16 isolates by microdilution method.

Almost all (n = 147) isolates were
, and remaining 2 isolates were
and unidentified, respectively. Based on molecular genotyping, all
isolates belonged to genotype 2. The MAC of 2 commonly used disinfectants, chlorhexidine and povidone-iodine, against 16
isolates was 1.56-3.13 and 48.83-390.63 µg/ml, respectively.

This report revealed for the first time the prevalence and the predominant
genotype 2 of bovine protothecal infection in Taiwan. In vitro algaecide efficacy indicated that both tested disinfectants were effective against
.
This report revealed for the first time the prevalence and the predominant P. zopfii genotype 2 of bovine protothecal infection in Taiwan. In vitro algaecide efficacy indicated that both tested disinfectants were effective against P. zopfii.
Screening of commercial mineral feeds and mineral licks on the German market containing selenium (Se) in relation to the Se status in equines in Thuringia with different forms of Se supplementation.

Commercially available Se-containing minerals for horses identified by an online research were evaluated for their Se concentration, Se source, flavour carrier and recommended dosage according to the manufacturer's labelling. Furthermore, serum Se status in 8 equine farms was regularly monitored over the period of one year. The sampled horses either received no Se supplement or Se was supplemented by a mineral lick, a mineral feed or supplementary feed.

In 29.7 % of the mineral licks, the manufacturers provided a label with information on the maximal daily Se dosage, all of which exceeded the current recommendations of daily Se intake for a 600 kg horse under maintenance conditions. According to the manufacturers' labelled dosage, 67.5 % of the mineral feeds also exceeded the recommended daily Se intake taking the daily Se requirement of a 600 kg horse under maintenance conditions into consideration.
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