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Link between Post-Operative Treatment using Concurrent Chemoradiotherapy (CRT) within High-Risk Resected Mouth area Squamous Mobile or portable Carcinoma (OCSCC): A new Multi-Institutional Cooperation.
Finally, we propose the direction for future works on MOF-based electrocatalysts. Copyright © 2019 American Chemical Society.In this short review, we draw parallels and stress differences between heart regeneration in mice and human, from a bioengineering perspective. As the prevailing dogma that the adult heart is completely post-mitotic is starting to change, there are multiple opportunities for augmenting the limited but definitive turnover of cardiomyocytes, to the extent necessary developing clinically relevant modalities for enhancing heart repair. We discuss some of the most promising among these new directions mobilization of paracrine signaling by therapeutic cells, cell-free therapy of the heart using extracellular vesicles, and direct reprograming of endogenous cells. These new directions share the cell-free, mechanistic approach to heart repair that could be translated into the clinic faster and safer than the traditional cell therapies.Design parameters for microphysiological systems (MPS) are driven by the need for new tools to answer questions focusing on human physiology in a robust and reliable manner. Within this perspective, engineering benchmarks and principles are identified to guide the construction of new devices in the MPS field, with emphasis placed on the design principles common to all tissues, as well as those unique to a subset of tissues. Leading organ replica technologies that recapitulate various functions of the brain, heart, intestine, and lung are highlighted as examples that meet the identified benchmarks and standards, with current barriers for large scale production and commercialization discussed. To reach their full potential and achieve widespread use, MPS will have to be recognized officially by government agencies, and toward this end, considerations of MPS as a potential regulatory tool are presented.Nutcracker syndrome is a rare vascular disorder that involves compression of the left renal vein (LRV), most often at the level of the aortomesenteric angle. In some cases, this compression syndrome arises in the setting of unusual vascular anatomic variants. We describe the case of a 43-year-old woman with a duplicated inferior vena cava who was found to have LRV compression on magnetic resonance angiography and venography with intravascular ultrasound. The patient was successfully treated with concurrent transposition of the LRV and left-sided inferior vena cava, with complete resolution of symptoms. © 2020 The Authors.A 44-year-old man presented with symptoms of intermittent ischemia of the right foot. Sunitinib Computed tomography scanning of the right foot revealed a talar beak that had a close anatomic relation with the dorsalis pedis artery. Duplex ultrasound performed during a symptomatic episode confirmed ischemia induced by severe vasospasm of the dorsalis pedis artery that normalized 30 minutes later. The talar beak was removed by open surgery that resulted in complete resolution of the patient's symptoms. A talar beak should be considered in intermittent ischemic complaints of the foot in patients without atherosclerosis. © 2019 The Authors.Complicated type B aortic dissection (TBAD) is a life-threatening condition requiring surgical intervention. One such complication in the acute or chronic setting is aneurysmal degeneration. The dissected aortic wall is weakened, and the pressures in the false lumen are often high. In the past decade, thoracic endovascular aortic repair (TEVAR) has become the treatment of choice for TBAD. TEVAR can be complicated by lack of false lumen thrombosis, increasing the risk of death. We present three cases of TBAD with patent false lumens after TEVAR that were treated by false lumen coil embolization. © 2020 The Authors.Late formation of pseudoaneurysm related to stent fracture is rarely described in the literature. We describe a case of spontaneous 8-cm femoral superficial artery pseudoaneurysm rupture that had developed from fracture of a stent implanted 3 years previously. Surgical repair was performed with fractured stent removal and reverse saphenous vein bypass. © 2019 The Author(s).A patient with a chronic postdissection distal arch aneurysm was treated with total arch replacement and frozen elephant trunk. Following uneventful initial recovery, the frozen elephant trunk appeared to be inadvertently perfusing the false lumen through an already present (in retrospect) intimal tear, resulting in rapid dilation of the false lumen and proximal compression of the graft. Treatment consisted, first, of endovascular redirection of flow toward the distal true lumen and, second, open surgical repair of the remaining type IV aneurysm. This case underlines the importance of scrutinizing preoperative imaging for correct use of the frozen elephant trunk. © 2019 The Author(s).Osteochondroma, the most common tumor of bone, is usually asymptomatic. Vascular complications are an atypical presentation and include true or false aneurysm formation, deep venous thrombosis, and arterial insufficiency. A review of the English literature identified 130 cases of osteochondroma-related vascular complications. We describe the case of a 38-year-old man presenting with left calf pain and swelling who was diagnosed with the rare constellation of a popliteal pseudoaneurysm and incidental peroneal vein thrombosis secondary to a fractured femoral sessile osteochondroma. This was treated with resection of the osteochondroma, excision of the aneurysm, and primary end-to-end anastomosis of the artery. © 2020 The Author(s).Bronchial artery aneurysm (BAA) is a rare vascular abnormality that may result in life-threatening bleeding if it is left untreated. We present the case of a 35-year-old man with a mediastinal BAA characterized by a short inflow artery segment and tortuous single outflow vessel. The patient's BAA was treated with a novel approach involving placement of a patent ductus arteriosus closure device in the short inflow segment as well as coil embolization of the outflow vessel, successfully excluding the BAA. Two-week follow-up revealed no flow in the embolized artery on computed tomography angiography. This case demonstrates the first successful use of a patent ductus arteriosus occluder device in the treatment of a mediastinal BAA with short inflow segment. © 2019 The Authors.
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