Notes

Observation with the effect of closed-loop well being management depending on an internet system within sufferers using peritoneal dialysis: any randomized tryout.
Due to the COVID-19 pandemic, many universities struggle to engage students while implementing a distance-based teaching/learning approach and to provide hands-on activities to students enrolled in STEM classes. Implementing service-focused activities that can be conducted by the students remotely can overcome these struggles. The goals of this study were to 1) implement citizen science activities focused on water quality using three commercially available low-cost test strips (21, 51, and 161) while teaching four undergraduate engineering courses at the University of Mississippi (UM) during a pandemic event, and 2) evaluate the acceptability and validate the results obtained. Eighty-five undergraduate students (citizen scientists) and five research scientists (control group) collected two water samples (with triplicates) after receiving detailed step-by-step written guidelines and video tutorials. One hundred twenty tap water samples were collected from private households across Lafayette County and its surrace-to-face classes.Foaming is a problem that affects the efficient and stable operation of the anaerobic digestion process. Roscovitine Characterizing foaming mechanisms and developing early warning and foaming control methods is thus critically important. This review summarizes the correlation of process parameters, state parameters, and microbial communities with foaming in anaerobic digesters; discusses the applicability of the above-mentioned multi-scale parameters and foaming potential evaluation methods for the prediction of foaming risk; and introduces the principles and practical applications of antifoaming and defoaming methods. Multiple causes of foaming in anaerobic digestion systems have been identified, but a generalizable foaming mechanism has yet to be described. Further study of the correlation between extracellular polymeric substances and soluble microbial products and foaming may provide new insights into foaming mechanisms. Monitoring the foaming potential (including the volume expansion potential) is an effective approach for estimating the risk of foaming. An in-situ monitoring system for determining the foaming potential in anaerobic digestion sites could provide an early warning of foaming risk. Antifoaming methods based on operating parameter management and process regulation help prevent foaming from the source, and biological defoaming methods are highly targeted and efficient, which is a promising research direction. Clarifying foaming mechanisms will aid the development of active antifoaming methods and efficient biological defoaming methods.Passing of pharmaceutical residues into environment in an uncontrolled manner as a result of continuous increase in drug consumption across the globe has become a threatening problem for the ecosystems and almost all living creatures. In this study, diclofenac (DCF), carbamazepine (CBZ), 17β-estradiol (17β-E2) and 17α-ethynylestradiol (EE2) belonging to different therapeutic classes were investigated simultaneously in advanced biological treatment and nature-based treatments during 12-months sampling campaign. In this context, behavior patterns of pharmaceutically active compounds (PhACs) throughout the both wastewater and sludge lines in advanced biological wastewater treatment plant (WWTP), wastewater stabilization pond (WSP) and constructed wetland (CW) were discussed in detail based on each treatment processes seasonally. Furthermore, statistically evaluated data obtained in full-scale WWTPs were compared with each other in order to determine the valid removal mechanisms of these pharmaceutical compounds.DCF (up to 15% decrease) and CBZ (up to 95% increase). Sorption and desorption behaviors of DCF and CBZ were also evaluated in the sludge treatment processes found in advanced biological WWTP. Percentages of originated extra annual average of pharmaceutical loads were calculated as 0.64% and 0.90% for DCF and CBZ, respectively in the advanced biological WWTP due to the sidestream caused by the sludge dewatering unit.A powerful simple biochar catalyst derived from nanocellulose was applied to the catalytic upcycling of waste plastics into H2 and liquid fuels for the first time. For the results from model low-density polyethylene (LDPE) pyrolysis, the C8-C16 aliphatics and monocyclic aromatics were dominant constitutes of the liquid product with the yields ranging from 22 to 68 wt%. At the temperature of 500 °C and biochar to LDPE ratio surpassing 3, the LDPE could be completely degraded into liquid and gas without wax production. A wax yield of 16 wt% was observed at the temperature of 450 °C and biochar to LDPE ratio of 4, which was dramatically lower than that (77 wt%) from the absence of biochar at the temperature of 500 °C. Up to 92 vol% of H2 was detected in the gaseous product with a yield of 36 wt%. The lower temperatures and higher biochar to LDPE ratios favored increasing the generation of H2 at the expense of light gas CnHm especially CH4. Moreover, this biochar catalyst was tested effectively to convert the real waste plastics including grocery bags and packaging tray into valuable liquid and H2-enriched gas.As a by-product in the pharmaceutical industry, antibiotic fermentation residue is expected to be able to be utilized after effectively removing the antibiotics. However, evaluation of the effect of fermentation residue application on soil, especially the in situ environmental consequences considering not only the antibiotic resistance gene (ARG) abundance but also the resistome risk, has still not been sufficiently evaluated. Herein, the impact of treated erythromycin fermentation residue (EFR) on the resistome and risk score in soybean planting soil was investigated. Treated EFR application with dosages of 3750 kg (EFR250) and 7500 kg (EFR500) per hm2 soil did not increase the diversity (Shannon index, 2.84-3.38) or relative abundance (0.086-0.142 copies/16S rRNA gene) of the soil resistome compared with the Control (CK 2.92-3.2, 0.088-0.096 copies/16S rRNA gene). Soil resistome risk scores calculated by metagenomic assembly, showing the dissemination potential of ARGs, ranged from 22.9 to 25.0, and were also not significantly different between treated EFR amended soil and the Control. Notably, the diversity of the resistome increased at the sprout stage (Mann-Whitney U test, P less then 0.05) and the abundance of some ARG types (macrolide-lincosamide-streptogramin, aminoglycoside and tetracycline, etc.) shifted along the course of soybean growth (Kruskal-Wallis test, P less then 0.05). Structural equation model analysis showed that the soybean growth period affected the composition of ARGs by affecting the microbial community, which was further supported by Procrustes analysis (P less then 0.05) and metagenomic binning. Our findings emphasized that soil ARG abundance and resistome risk did not increase during one-time field application of treated EFR at the studied dosage. Comprehensive consideration including resistome risk and multiple influencing factors also should be given for further assessment of fermentation residue application.The current decline of invertebrates worldwide is alarming. Several potential causes have been proposed but metal pollutants, while being widespread in the air, soils and water, have so far been largely overlooked. Here, we reviewed the results of 527 observations of the effects of arsenic, cadmium, lead and mercury on terrestrial invertebrates. These four well-studied metals are considered as priorities for public health and for which international regulatory guidelines exist. We found that they all significantly impact the physiology and behavior of invertebrates, even at levels below those recommended as 'safe' for humans. Our results call for a revision of the regulatory thresholds to better protect terrestrial invertebrates, which appear to be more sensitive to metal pollution than vertebrates. More fundamental research on a broader range of compounds and species is needed to improve international guidelines for metal pollutants, and to develop conservation plans to protect invertebrates and ecosystem services.Nitrous oxide (N2O) is a strong greenhouse gas produced by biotic/abiotic processes directly linked to both fungal and prokaryotic communities that produce, consume or create conditions leading to its emission. In soils exposed to nitrogen (N) in the form of urea, an ecological succession is triggered resulting in a dynamic turnover of microbial populations. However, knowledge of the mechanisms controlling this succession and the repercussions for N2O emissions remain incomplete. Here, we monitored N2O production and fungal/prokaryotic community changes (via 16S and 18S amplicon sequencing) in soil microcosms exposed to urea. Contributions of microbes to emissions were determined using biological inhibitors. Results confirmed that urea leads to shifts in microbial community assemblages by selecting for certain microbial groups (fast growers) as dictated through life history strategies. Urea reduced overall community diversity by conferring dominance to specific groups at different stages in the succession. The diversity lost under urea was recovered with inhibitor addition through the removal of groups that were actively growing under urea indicating that species replacement is mediated in part by competition. Results also identified fungi as significant contributors to N2O emissions, and demonstrate that dominant fungal populations are consistently replaced at different stages of the succession. These successions were affected by addition of inhibitors which resulted in strong decreases in N2O emissions, suggesting that fungal contributions to N2O emissions are larger than that of prokaryotes.
To describe the laterally extended parametrectomy (LEP) surgical technique, emphasizing the main challenges of the procedure.

LEP was designed as a more radical surgical procedure aiming to remove the entire parametrial tissue from the pelvic side wall. Its initial indications were for lymph node positive Stage Ib (current FIGO 2018 Stage IIIc) and Stage IIb cervical cancer. Currently, with most guidelines recommending definitive radiochemotherapy for these cases, initial LEP indications have become debatable. LEP is now mainly indicated for removing tumors involving the soft structures of the pelvic side wall during a pelvic exenteration, aiming to obtain lateral free margins. This expands the lateral borders of the dissection to not only the medial surface of internal iliac vessels, but also to the true limits of the pelvic side wall.

During LEP, the parietal and visceral branches of the hypogastric vessels are divided at the entry and exit level of the pelvis. Consequently, the entire internal iliac system is excised, and no connective or lymphatic tissue remain on the pelvic side wall. The main technical challenges of LEP are caused by the difficulty in ligating large caliber vessels (internal iliac artery and vein) and the variable anatomic distribution of pelvic side wall veins.

LEP is a feasible technique for removing pelvic side wall recurrences, aiming to obtain surgical free margins.
LEP is a feasible technique for removing pelvic side wall recurrences, aiming to obtain surgical free margins.
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