Notes

Next-generation multimodality of nutrigenomic cancer malignancy treatments: sulforaphane together with acetazolamide make an effort to targeted bronchial carcinoid cancer inside debilitating your PI3K/Akt/mTOR success path as well as inducing apoptosis.
Results indicate that a bifactor structure modeling D along with five specific factors-or themes-labeled Callousness, Deceitfulness, Narcissistic Entitlement, Sadism, and Vindictiveness, best describes the internal structure of D. (PsycInfo Database Record (c) 2021 APA, all rights reserved).The International Classification of Diseases-11th Edition (ICD-11) includes a dimensional trait model of personality disorder. The Personality Inventory for ICD-11 (PiCD) was the first self-report measure developed for its assessment. The present study examines the validity of an informant-report version of the PiCD, the Informant-Personality Inventory for ICD-11 (the IPiC), and is the first study to test self-other agreement, ratings from close others, and the criterion validity of both the IPiC and the PiCD for several popular and well-validated measures of life functioning Life and romantic relationship satisfaction, social support, physical and mental health, depressive symptoms, insomnia symptoms, and cognitive decline. The present study is also the first to examine the IPiC and PiCD in a sample of older adults in the community. Results suggest that the IPiC and the PiCD show moderate self-other agreement, are associated significantly with several important life functioning areas, and have structural validity even at the item level. Further replication and validation are necessary for these instruments, but the IPiC and the PiCD have shown strong validation evidence to date, now including evidence of consensual and criterion validity, in addition to structural validity. (PsycInfo Database Record (c) 2021 APA, all rights reserved).Toward better understanding the determinants of harsh parenting, the present study assessed prospective associations between mothers' and fathers' sleep problems and their harsh parenting toward their child using two waves of data. Children's gender was examined as a moderator of these associations. At the first wave, 257 families participated. Mean age was 36.15 years (SD = 5.70 years) for mothers, 39.78 years (SD = 7.54 years) for fathers, and 10.41 years (SD = 7.85 months) for children. The sample was diverse in terms of race/ethnicity and socioeconomic status with approximately 68% identifying as White/European American and 29% identifying as Black/African American. After approximately 1 year, families participated in a second study wave. Parents' sleep was assessed using actigraphy (sleep minutes, sleep efficiency, and long wake episodes) and mothers and fathers reported on the occurrence of their psychological and physical forms of harsh parenting toward their child. After controlling for autoregressive effects, fewer sleep minutes, reduced sleep efficiency, and more frequent long wake episodes among fathers predicted greater harsh parenting among fathers 1 year later. Child gender moderated some of these associations such that relations between fathers' poorer-quality sleep and higher levels of harsh parenting were more pronounced for boys. Sleep problems among mothers did not predict mothers' harsh parenting over time. Findings build on a growing literature that has considered sleep in the family context and provide novel insight into the influence of parents' sleep on their parenting practices. (PsycInfo Database Record (c) 2021 APA, all rights reserved).Nostalgia, the fond remembrance of one's past, is a common experience hypothesized to increase across the life span. Yet data on the specific features of nostalgia, such as daily frequency and associated affect, are scarce. This study sought to address this limitation by assessing the daily experience of nostalgia using experience-sampling methods. A life-span sample of 108 participants (47 young, 31 middle-aged, and 30 older adults) completed a 2-week, twice-daily experience-sampling study that yielded data describing the frequency and emotions of everyday nostalgia. Foxy-5 datasheet Multilevel logistic regression analyses supported increased nostalgia frequency at every life stage Young adults were 60% less likely to report nostalgia compared with middle-aged adults (odds ratio [OR] = .40), whereas older adults were 3 times more likely than middle-aged adults to report nostalgia (OR = 3.05). Additionally, the experience of nostalgia was associated with significant heterogeneity in positive and negative affect. Approximately 72% of participants experienced an increase in positive affect, and 51% experienced an increase in negative affect. For young and middle-aged adults, a change in positive affect was associated with a 2-times-larger increase in nostalgia likelihood, whereas a change in negative affect was more strongly associated with a nostalgia experience in older adults. The current study provides increased evidence for the affectively mixed nature of nostalgia and how the affective pattern differs for adults of different ages. Greater nostalgia frequency may be instrumental during life review when individuals make meaning of their lives, fulfilling developmental goals of late adulthood. (PsycInfo Database Record (c) 2021 APA, all rights reserved).People take longer to determine that metaphoric sentences (e.g., some birds are flutes) are literally false compared to anomalous sentences (e.g., some birds are pickles). This metaphor interference effect (MIE) shows that metaphorical interpretations are automatically computed even in contexts and tasks that only require literal interpretations. Although a well-replicated finding, the MIE has only been investigated in sentence stimuli in which the metaphoric composition is explicitly stated (such that birds are asserted to be flutes). This raises questions about the generalizability of the MIE because (a) A is B metaphors are rare in discourse and (b) other metaphor variants, such as flute bird, are unspecified in their metaphoric composition (i.e., do not specifically assert which concept, if any, is metaphorical). In this experiment, we investigated whether metaphoric modifier-noun phrases such as flute bird and creamy sky produce a MIE. In addition, we explored if word-level semantic variables (semantic neighborhood density and concreteness) play a role in the MIE. We asked participants to determine if modifier-noun phrases refer to things that literally exist or not. We found a MIE in which metaphoric phrases (e.g., flute bird, creamy sky) took longer to judge as literally false relative to scrambled counterparts (e.g., flute sky, creamy bird). Moreover, we found that word-level semantic variables affect the magnitude of the MIE only for adjective-noun phrases. Therefore, metaphoric meaning can be automatically extracted from metaphoric compounds, suggesting that the MIE is more robust than previously demonstrated. (PsycInfo Database Record (c) 2021 APA, all rights reserved).In backward immediate serial recall, participants recall lists of items immediately after their presentation by beginning with the last presented item and ending with the first presented one. Despite the similarities with forward recall in which participants recall the items from the first to the last presented, benchmark memory phenomena reliably found in forward recall are not constantly observed in backward recall. Here, we proposed a new framework called the encoding-retrieval matching (ERM) hypothesis to account for backward recall. The ERM retains the main features of the visuospatial hypothesis and the item-order trade-off hypothesis, the two dominant accounts of backward recall. According to the ERM, output modality and foreknowledge of recall direction influence the availability of visuospatial representations and the weight devoted to item and order processing. We tested the ERM with irrelevant speech, a well-known working memory factor disrupting forward recall. In two experiments, we manipulated recall direction (forward vs. backward), irrelevant speech (control vs. irrelevant speech), and response modality (manual vs. oral). As predicted by the ERM, when recall direction was unpredictable in Experiment 1, the magnitude of the irrelevant speech effect was larger in backward manual recall than in backward oral recall. In Experiment 2, recall direction was predictable. As predicted by the ERM, in backward recall, the irrelevant speech effect was reduced with a manual response and absent with an oral response. We concluded that ERM effectively accounts for the complex interplay between response modality, foreknowledge of recall direction, and benchmark memory effects in backward recall. (PsycInfo Database Record (c) 2021 APA, all rights reserved).There has been increasing recognition that classically defined psychiatric disorders cluster hierarchically. However, the degree to which this hierarchical taxonomy manifests in the distribution of one's daily affective experience is unknown. In 462 young adults, we assessed psychiatric symptoms across internalizing and externalizing disorders and then used cell-phone-based ecological momentary assessment (EMA) to assess the distribution (mean, standard deviation, skew, kurtosis) of one's positive and negative affect over 3-4 months. Psychiatric symptoms were modeled using a higher-order factor model that estimated internalizing and externalizing spectra as well as specific disorders. Individualized factor loadings were extracted, and path models assessed associations between spectra and syndromes, and daily affect. Internalizing and externalizing spectra displayed broad differences in the distribution of affective experiences, while within the internalizing spectrum, syndromes loading onto fear and distress subfactors were associated with distinct patterns of affective experiences. (PsycInfo Database Record (c) 2021 APA, all rights reserved).In this study, we conducted a citation network analysis of the Journal of Counseling Psychology (JCP) to elucidate the scope, evolution, and interconnections of JCP publications as reflected in how authors use (i.e., cite) these publications. We used CitNetExplorer to analyze a network of 4,718 JCP publications and 16,959 citation links. The analysis yielded 19 clusters in JCP's citation network. The most dominant facet of the citation network focused on counseling, counseling process, and counseling outcome. The clusters in this facet shifted from an early focus on perceptions of counselors to continuing examinations of what happens in counseling. Another dominant facet comprised clusters on vocational psychology, shifting from an earlier focus on vocational choice and interest, to career counseling and decision making, to vocational and academic development processes and predictors. These major facets converged toward a continuing cluster focused on methodology and analysis along with race, gender, sexuality, and other diversity scholarship. This suggests that diversity-focused publications in JCP often employ and cite methodological and analytic advances. The results also reveal discontinued areas of scholarship in JCP that are ripe for revisiting and rebuilding in new directions (e.g., anger and social justice activism; clinical judgment and artificial intelligence). The results suggest that a promising next step in the evolution of JCP would be for authors to engage with and cite diversity scholarship as central to "general" domains of JCP scholarship. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
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