Notes

HDAC6 inactivates Runx2 marketer to bar osteogenesis regarding navicular bone marrow stromal cellular material inside age-related navicular bone loss in these animals.
04, 89.52, and 93.01, respectively. That outperforms 5 recent and state-of-the-art (SOTA) eye blink detection algorithms.

The proposed method is robust in eye blink artifact detection for EEGs containing high-frequency epileptiform discharges. It is also effective in dealing with individual differences in EEGs, which is usually ignored in conventional methods.
The proposed method is robust in eye blink artifact detection for EEGs containing high-frequency epileptiform discharges. It is also effective in dealing with individual differences in EEGs, which is usually ignored in conventional methods.Previous studies have demonstrated that the stability changes in physiological signals can reflect individuals' pathological conditions. Apart from this, according to system science theory, a large-scale system can generally be divided into many subsystems whose stability level govern its overall performance. Therefore, this study attempts to investigate the possibility of analyzing the stability of decomposed subsystems of resting-state fMRI (rs-fMRI) BOLD signals in order to assess the overall characteristic of the human brain and individuals' health conditions. We used attention deficit/hyperactive disorder (ADHD) as an example to illustrate our method. Rs-fMRI BOLD signals were first decomposed into dynamic modes (DMs) which can illuminate the patterns of brain subsystems. Each DM is associated with one eigenvalue that determines its stability as well as oscillation frequency. Accordingly, we divided the DMs within common BOLD frequency bands into stable and unstable DMs. Then, the features related to the stability of those DMs were extracted, and nine common classifiers were used to differentiate healthy controls from ADHD patients taken from ADHD-200, a well-known dataset. The results showed that almost all features were statistically significant. Additionally, our proposed approach outperforms all existing methods with the highest possible precision, recall, and area under the receiver operating characteristic curve of 100%. In sum, we are the first to evaluate the stability of BOLD signals and demonstrate its possibility for disease diagnosis. This method can unveil new mechanisms of brain function, and could be widely used in medicine and engineering.Comprehensively evaluating and comparing researchers' academic performance is complicated due to the intrinsic complexity of scholarly data. Different scholarly evaluation tasks often require the publication and citation data to be investigated in various manners. In this paper, we present an interactive visualization framework, SD^2, to enable flexible data partition and composition to support various analysis requirements within a single system. SD^2 features the hierarchical histogram, a novel visual representation for flexibly slicing and dicing the data, allowing different aspects of scholarly performance to be studied and compared. We also leverage the state-of-the-art set visualization technique to select individual researchers or combine multiple scholars for comprehensive visual comparison. We conduct multiple rounds of expert evaluation to study the effectiveness and usability of SD^2 and revise the design and system implementation accordingly. The effectiveness of SD^2 is demonstrated via multiple usage scenarios with each aiming to answer a specific, commonly raised question.Glass is very common in the real world. Influenced by the uncertainty about the glass region and the varying complex scenes behind the glass, the existence of glass poses severe challenges to many computer vision tasks, making glass segmentation as an important computer vision task. Glass does not have its own visual appearances but only transmit/reflect the appearances of its surroundings, making it fundamentally different from other common objects. To address such a challenging task, existing methods typically explore and combine useful cues from different levels of features in the deep network. As there exists a characteristic gap between level-different features, i.e., deep layer features embed more high-level semantics and are better at locating the target objects while shallow layer features have larger spatial sizes and keep richer and more detailed low-level information, fusing these features naively thus would lead to a sub-optimal solution. In this paper, we approach the effective features fusion to-edge models on three challenging datasets under four standard metrics. The code and dataset will be made publicly available.Deep neural networks have achieved remarkable progress in single-image 3D human reconstruction. However, existing methods still fall short in predicting rare poses. The reason is that most of the current models perform regression based on a single human prototype, which is similar to common poses while far from the rare poses. In this work, we 1) identify and analyze this learning obstacle and 2) propose a prototype memory-augmented network, PM-Net, that effectively improves performances of predicting rare poses. The core of our framework is a memory module that learns and stores a set of 3D human prototypes capturing local distributions for either common poses or rare poses. With this formulation, the regression starts from a better initialization, which is relatively easier to converge. Extensive experiments on several widely employed datasets demonstrate the proposed framework's effectiveness compared to other state-of-the-art methods. Notably, our approach significantly improves the models' performances on rare poses while generating comparable results on other samples.Energy-based ultrasound elastography techniques minimize a regularized cost function consisting of data and continuity terms to obtain local displacement estimates based on the local time-delay estimation (TDE) between radio frequency (RF) frames. The data term associated with the existing techniques takes only the amplitude similarity into account and hence is not sufficiently robust to the outlier samples present in the RF frames under consideration. This drawback creates noticeable artifacts in the strain image. To resolve this issue, we propose to formulate the data function as a linear combination of the amplitude and gradient similarity constraints. We estimate the adaptive weight concerning each similarity term following an iterative scheme. Finally, we optimize the nonlinear cost function in an efficient manner to convert the problem to a sparse system of linear equations which are solved for millions of variables. We call our technique rGLUE robust data term in GLobal Ultrasound Elastography. rGLUE has been validated using simulation, phantom, in vivo liver, and breast datasets. AZ 960 ic50 In all our experiments, rGLUE substantially outperforms the recent elastography methods both visually and quantitatively. For simulated, phantom, and in vivo datasets, respectively, rGLUE achieves 107%, 18%, and 23% improvements of signal-to-noise ratio (SNR) and 61%, 19%, and 25% improvements of contrast-to-noise ratio (CNR) over global ultrasound elastography (GLUE), a recently published elastography algorithm.Synthesizing a subject-specific pathology-free image from a pathological image is valuable for algorithm development and clinical practice. In recent years, several approaches based on the Generative Adversarial Network (GAN) have achieved promising results in pseudo-healthy synthesis. However, the discriminator (i.e., a classifier) in the GAN cannot accurately identify lesions and further hampers from generating admirable pseudo-healthy images. To address this problem, we present a new type of discriminator, the segmentor, to accurately locate the lesions and improve the visual quality of pseudo-healthy images. Then, we apply the generated images into medical image enhancement and utilize the enhanced results to cope with the low contrast problem existing in medical image segmentation. Furthermore, a reliable metric is proposed by utilizing two attributes of label noise to measure the health of synthetic images. Comprehensive experiments on the T2 modality of BraTS demonstrate that the proposed method substantially outperforms the state-of-the-art methods. The method achieves better performance than the existing methods with only 30% of the training data. The effectiveness of the proposed method is also demonstrated on the LiTS and the T1 modality of BraTS. The code and the pre-trained model of this study are publicly available at https//github.com/Au3C2/Generator-Versus-Segmentor.Registration of multiple stained images is a fundamental task in histological image analysis. In supervised methods, obtaining ground-truth data with known correspondences is laborious and time-consuming. Thus, unsupervised methods are expected. Unsupervised methods ease the burden of manual annotation but often at the cost of inferior results. In addition, registration of histological images suffers from appearance variance due to multiple staining, repetitive texture, and section missing during making tissue sections. To deal with these challenges, we propose an unsupervised structural feature guided convolutional neural network (SFG). Structural features are robust to multiple staining. The combination of low-resolution rough structural features and high-resolution fine structural features can overcome repetitive texture and section missing, respectively. SFG consists of two components of structural consistency constraints according to the formations of structural features, i.e., dense structural component and sparse structural component. The dense structural component uses structural feature maps of the whole image as structural consistency constraints, which represent local contextual information. The sparse structural component utilizes the distance of automatically obtained matched key points as structural consistency constraints because the matched key points in an image pair emphasize the matching of significant structures, which imply global information. In addition, a multi-scale strategy is used in both dense and sparse structural components to make full use of the structural information at low resolution and high resolution to overcome repetitive texture and section missing. The proposed method was evaluated on a public histological dataset (ANHIR) and ranked first as of Jan 18th, 2022.In clinical practice, multi-modal magnetic resonance imaging (MRI) with different contrasts is usually acquired in a single study to assess different properties of the same region of interest in the human body. The whole acquisition process can be accelerated by having one or more modalities under-sampled in the k -space. Recent research has shown that, considering the redundancy between different modalities, a target MRI modality under-sampled in the k -space can be more efficiently reconstructed with a fully-sampled reference MRI modality. However, we find that the performance of the aforementioned multi-modal reconstruction can be negatively affected by subtle spatial misalignment between different modalities, which is actually common in clinical practice. In this paper, we improve the quality of multi-modal reconstruction by compensating for such spatial misalignment with a spatial alignment network. First, our spatial alignment network estimates the displacement between the fully-sampled reference and the under-sampled target images, and warps the reference image accordingly.
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