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(Gambar 3: Mekanisme Kerja Nitric Oxide di dalam tubuh manusia)
Produksi Nitric Oxide juga menyebabkan pelebaran pembuluh darah paru, sehingga meningkatkan saturasi oksigen sehingga memperbaiki pernafasan yang lebih baik. Demikian pula pada pembuluh darah secara keseluruhan, sehingga bisa menjadi anti hipertensi yang efektif menurunkan hipertensi. Demikian pula karena peningkatan vitalitas pembuluh darah, menyebabkan perbaikan kemampuan erektil atau rangsangan ereksi pada laki-laki. Hal ini diperkuat dengan meningkatkan sinyal melalui jalur Nitric Oxide pada penis.
Fungsi yang lain dari senyawa Nitric Oxide, sebagai bagian dari respon kekebalan tubuh manusia. Kekebalan tubuh meningkat atas peran Nitric Oxide yang dapat mengaktifkan interferon-gamma (IFN-γ) dan interleukin-4 (IL-4), dengan cara ini sistem kekebalan tubuh akan meningkat. Demikian pula berefek untuk mempercepat penyembuhan pembengkakan tubuh ( anti inflamasi)
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