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https://en.wikipedia.org/wiki/Leukotriene

There are many contributors to the inflammatory process, and prostaglandins are one of the more significant ones. Prostaglandins are one of the more potent mediators that cause increased blood flow, chemotaxis (chemical signals that summon white blood cells), and subsequent dysfunction of tissues and organs. They are a body's response to noxious agents, and as long as the noxious agents persist, prostaglandins will continue to be produced and add to the inflammatory process.

     
 
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