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- The parents of the affected individual are typically genetically normal.[4] The extra chromosome occurs by random chance.
- There is no known behavioral activity or environmental factor that changes the risk.
- Down syndrome can be identified during pregnancy by prenatal screening followed by diagnostic testing or after birth by direct observation and genetic testing.
- There is no cure for Down syndrome.
- Some children with Down syndrome are educated in typical school classes, while others require more specialized education.
- Down syndrome is one of the most common chromosome abnormalities in humans. It occurs in about one per 1000 babies born each year. In 2013, Down syndrome was present in 8.5 million individuals and resulted in 36,000 deaths down from 43,000 deaths in 1990.[16][17] It is named after John Langdon Down, the British doctor who fully described the syndrome in 1866.
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