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Anti-Cancer Influence Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Breast Cancer




Xao tam phan (Paramignya trimera (Oliv.) Guillaum) is often a Vietnamese traditionally medicinal plant found in the treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This research aimed to analyze the results of 5 various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The final results indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the greatest antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (aside from total flavonoids) and antioxidant capacity, in comparison to conventional and ultrasound-assisted extractions. These data show the application of methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application from the nutraceutical and/or pharmaceutical industries.





Drying methods, solvents and extraction methods greatly get a new phytochemical compounds and biological activity from plant materials. The aims with this study could determine the consequences of various drying methods, various solvents and extraction methods around the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root from Vietnam. The results demonstrated that microwave drying was an efficient method in removal of water when it comes to shortest drying time, lowest energy consumption as well as retention of phytochemical compounds and antioxidant capacity in the P. trimera root while methanol and microwave-assisted extraction were the very best solvent and means for greatest extraction of the phytochemical compounds and antioxidant capacity from your P. trimera root. The findings out of this study allow retaining the best degrees of phytochemical compounds and antioxidant capacity from the P. trimera root for potential application in the nutraceutical industry.


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