Notes

Potency drugs on prescription


As a rule, so-called phosphodiesterase-5 inhibitors, PDE-5 inhibitors for short , are meant by sexual enhancers. They are the first choice to treat erectile dysfunction in most cases .

PDE-5 inhibitors dilate the vessels in the erectile tissue and relax the muscles, allowing more blood to flow into the erectile tissue in the penis . Due to their vasodilating effect, they are also used to treat high blood pressure or benign prostate enlargements .

Potency drugs are generally subject to prescription in Germany, as they can have various side effects and not everyone can take them. Erection problems are often psychological and not physical. Potency pills should therefore usually only be taken temporarily.


PDE-5 inhibitors

The first drug of this type to be approved is Sildenafil. Sildenafil was launched in 1998 under the name Viagra.

They work against the enzyme phosphodiesterase-5 (PDE-5), which breaks down the messenger substance cyclic guanosine monophosphate (cGMP). This messenger causes the vascular muscles to relax, which causes the vessels to expand and blood flow to improve. When you are sexually aroused, this means that more blood gets into the erectile tissue in the penis, resulting in an erection. The erection becomes stronger and lasts longer. The active substance cannot trigger an erection. The drugs do not generally increase sexual desire. An erection only comes about under sexual arousal.

PDE-5 inhibitors include:

Sildeanfil (Viagra, various generics)

Tadalafil (Cialis, various generics)

Vardenafil (Levitra, various generics)

Avanafil (Spedra)

Prescription drugs for erectile dysfunction
Sildenafil AbZ film-coated tablets packaging front
Sildenafil ratiopharm film-coated tablets packaging front
Tadalafil ratiopharm film-coated tablets packaging front
Sildenafil Basics 100 mg film-coated tablets packaging front
Viagra film tablets packaging front
Cialis film-coated tablets packaging front

Since PDE-5 inhibitors are generally considered to be well tolerated, have been very well researched and can also be taken long-term, other prescription-only alternatives such as alprostadil and apomorphine are the exception.
Alprostadil

The active ingredient alprostadil is occasionally used as an alternative to PDE5 inhibitors. 비아그라 of this active ingredient is unusual for this indication and usually only occurs when other sexual enhancers have had no effect or are not allowed to be taken.

Alprostadil is the synthetic alternative to the body's own prostaglandin E1 . It promotes blood circulation and inhibits clotting. The advantage compared to other remedies is that it can also be used for erectile dysfunction caused by nerve damage.

Alprostadil must be applied locally. This means that the active substance must either be injected directly into the erectile tissue of the penis (SKAT, erectile tissue autoinjection therapy) or inserted and placed in the urethra as a urethral rod (MUSE, drug urethral system for erection). Due to the painful application and the high risk of overdose or injury, self-administration must first be specially learned.
apomorphine

Apomorphine is a sexual enhancer that was originally used as an aporphine alkaloid against poisoning and is now mainly prescribed for Parkinson's therapy. Coincidentally, it was found that the active ingredient in small doses also has an erection-stimulating effect.

In contrast to PDE-5 inhibitors, however, apomorphine directly stimulates the corresponding regions in the central nervous system and does not affect individual messenger substances.

In 2001, it was approved as a prescription drug for erectile dysfunction in Germany. After almost four years, however, both available drugs were withdrawn from the market due to a lack of sales.

Apomorphine continues to be researched as a sexual enhancer.
Over-the-counter sexual enhancers

In addition to the classic potency pills, there are many suppliers of alternative medicines and dietary supplements for erection problems on the market .

The effect of natural sexual enhancers has not been scientifically proven. If you are looking for over-the-counter sexual enhancers with an immediate effect, you will unfortunately be disappointed.

However, some of the sexual enhancers that are available without a prescription contain active ingredients that have a positive effect on potency. An example of this are over-the-counter sexual enhancers that promote blood circulation. Foods high in antioxidants, such as blackberries or green tea, can also help prevent impotence .

The most common active ingredients in over-the-counter sexual enhancers are:

Turnera diffusa (Damiana)

arginine

maca

yohimbine

Turnera diffusa

Turnera diffusa is the Latin name of the damiana, a plant that is mainly found in southern North America to South America. Like some other plants of the saffron mallow genus, it is said to have an aphrodisiac effect.

As with most natural sexual enhancers, an actual effect has not been scientifically proven . However, studies, including those on rats, suggest that Turnera diffusa influences the sex hormone progesterone and thus has a positive effect on potency.
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