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Patients with MAS will experience both symptoms and signs of HLH, as they have a deficiency in either gene. The disease often manifests in the early stages, but it can recur if the patient has the mutation. Although it is not always possible to determine whether a patient has MAS by examining the patient, there are several clinical indicators that are helpful in establishing a diagnosis. For example, a mild hemophagocytic change may indicate that the patient has MAS.

MAS is considered a secondary form of HLH. In contrast to primary genetic HLH, MAS shares many clinical features with other forms. Cytotoxic defect results from heterozygosity of the pHLH gene mutations, infection, or underlying inflammation. Most cases of MAS occur during active disease phases, so it is essential to assess the inflammatory status of the patient before pursuing treatment. The severity of the disease can vary from mild to severe, and it is important to know if your symptoms are a sign of MAS.

There are two types of immunity in the human body: the innate and adaptive. The innate immune system launches a general response to invading organisms. In MAS, the innate immune system responds by launching specific antibodies against specific infections. To fight infections, different types of immune cells work together. Macrophages, which attack viruses, attack bacteria, and gather T-lymphocytes, which sends signals to gather them. However, the innate immune system fails to destroy the infectious cells. Moreover, it floods the body with inflammatory cytokines, which can damage any organ.

The innate immune system works in two ways. The innate immune system initiates a general response to invading organisms. The adaptive immune system launches specific antibodies against specific bacteria and viruses. During an outbreak of MAS, the inflammatory response is overactive. The inflammatory response is the most common cause of the disease. The innate immune system will overreact to the infection. It is the first line of defense in the body.

MAS is caused by an overactive innate immune system. This immune system will cause the body to produce more inflammatory cytokines than normal. The innate immune system has two main parts. The innate immune system consists of the innate immune system. It starts the inflammatory response by launching specific antibodies. The innate immune cell, or macrophage, kills the infected cells. The adaptive immune cell, or T-lymphocytes, then send signals to the macrophages. If these cells can't eliminate the infected cells, it will flood the body with inflammatory cytokines, which can lead to serious complications.

MAS is caused by an overactive innate immune system. It is a common reaction to invading organisms. The innate immune system has a wide range of functions, and it is often overactive. It has a broad role in fighting infections. It creates specific antibodies against viruses, bacteria, and fungi. It can also destroy cells in the body. It also attacks the tissues and organs, causing inflammation.

MAS is characterized by an overactive innate immune system. In a healthy body, it responds to invading organisms by launching a generalized response and producing specific antibodies against invading microorganisms. In a healthy person, the innate immune system will produce a variety of different types of cytokines, which will help the body to fight infections. When the innate immune system is overactive, it will overwhelm the host's innate immune system.

During an infection, the immune system will launch a general response to an invading organism. The innate immune system is overactive and will create multiple antibodies to fight an infection. This causes MAS. The innate immune system can cause various illnesses, ranging from rheumatoid arthritis to AIDS. Generally, this system will attack infected cells with the help of NK cells and macrophages.
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