Notes

Could Weed Cure Depression?
1 in 4 Canadians suffer from depression sufficient to need therapy. There are many different treatments for depression; medical cannabis is becoming more popular these days.

What are the signs of depression?

Depression can be devastating depending on the severity of the condition. There are three kinds of depression - major depressive disorder , dysthymia and bipolar disorder.

A person with major depressive disorder may experience sad all the time, cranky, hopeless and cannot handle the pressure.

Dysthymia (depressive neurosis) - It can be confused with other forms of mental or physical illness.

Bipolar depression a person may have a high and low feeling.

Depression can also cause changes in sleeping routine, a change in appetite and some individuals put on body weight and other has an eating habit difficulty, some are unable to focus. Some feel unworthy and guilty; some may hear unreal voices that can lead them to self-destructive instinct.

When should a depress person seek a doctor’s support?

Depression and sad days are common aspect of our lives. Healthy people go through periods of low mood, low energy and unhappiness. When these problems become chronic or you begin to feel everything is not good, call to see a doctor. Unfavorable feelings should not have a big impact on your life. If you experience that your negative mind, moods or emotions are always impacting your quality of life or relationships, it is crucial to look for help.

Could cannabis be used to treat depression?

The response is YES!, cannabis medicine can be very valuable treatment option for depression. It can be used individually of other medications, or with other conventional pharmacological agents. Medical cannabis should always be used in conjunction with things like healthy diet, exercise, sleep hygiene meditation, mindfulness and psychological strategies.

Cannabis functions by acting upon and up managing the endocannaboid system or ECS. ECS is important for maintaining stability and homeostasis within the body. Researcher talk about ECS’s main functions as sleep, relax, eat, protect and forget.



Should medical cannabis be recommended for depression?

In Canada, medical cannabis can be prescribed for depression. Just be sure that you are buying from the authorized dealer.

How does cannabis impact depression and how does THC help with depression?

THC itself can be a beneficial treatment for depression as THC immediately stimulates the body’s own cannabinoid receptors. When used correctly, THC has similar effects to our own internal, or endogenous, cannabinoid Anandamide.

Anandamide is the body’s naturally occurring cannabinoid-like molecule, which can be connected to boost in energy or euphoric state we presume of as ‘runner’s high. THC can help to enhanced mood, it can breakdown ruminating feelings and negative thoughts. It can also assist regulate sleep. Study shows that THC may help reduce the affect of or replaying of traumatic memory.

Can THC make depression worse?

It can make depression worse, depends on the individuals and the volume to use. Cannabis and cannabinoids will not work the same for everyone. For certain individuals, under certain situations, THC can trigger dysphoria, which can aggravate the mood.

For most people undergo an uplifting of their mood or more of euphoria, which helpful for depression. Various individuals are not able to tolerate THC, and for others, high dosage can actually lower-regulate the body’s own endocannabinoid function. Due to the fact the ECS is very important in mood regulation, causing a down-regulation can lead to worsening mental health.

Any of those who get a failing of mood are the minority. It is important when starting a cannabis treatment, be careful with your THC dosage. Too much THC or too frequent use of THC can badly affect the ECS.


Cannabis and CBD oil for depression

Cannabidiol (CBD) and CBD oil can be a very helpful treatment for depression. CBD is a cannabinoid that is compatible on about 60 different receptors, enzymes and neurotransmitter. It also can activate adenosine pathway which help with relaxation and serotonin pathways which can help in increase mood. As low dopamine and serotonin can result certain problems of depression, control of these chemicals is important. CBD can help prevent the re-uptake of neurotransmitters like serotonin, dopamine and GABA which indicates that your body can use those chemicals for longer periods.


Which terpenes help with depression?

Terpenes can be useful in treating depression. It has the essential oils in cannabis and gives the various kinds of aromas. However, most research that is been done is on mice, not on humans. Some terpenes that are good for anxiety and depression are:

Limonene – research shows it may reduce stress and anxiety

Pinene – research shows it has an anxiety reducing effect


Linalool – research shows that the odor can have anxiety reducing effect

Mercene – research shows that it has a sedative effect



Side effects of using cannabis for depression

The majority of medications can have side effects and cannabis is no different. The unwanted effects of cannabis are quite mild and usually well tolerated.

THC can cause some dysphoria and a change of state in mood for certain people who are not used to THC or are intolerant of THC. It can also build up fatigue or slow down mental processing. Therefore, if an person is having problems with fatigue and trouble thinking, then THC can have an additive effect to those symptoms.

CBD on the contrary is generally very well tolerated. CBD, at higher doses, can cause a bit of a hyperarousal, which lead to even more troubles in sleep. If people are consuming high dose of CBD just before bed, it can really interrupt some of the sleep structure and affect REM sleep.

Keep in mind that every person is different and so the side effects may vary. Cannabis doesn’t work for most people.


So what does the research say about cannabis and depression?

Truth be told there is a lack of good quality medical trials particularly looking at depression or improvements in depression as their major results. There are some mouse test which show that cannabis can help with depression . Other studies have demonstrated significant progress in well being for individuals using cannabis medicines.

Recently there is also a lot of case based information, which means individual doctor-patient cases where cannabis is helping with depression. Lastly, there were studies that show the ECS role in depression which shows there is a link amongst endocannabinoid dysfunction and depression.

Cannabis is not a first or second line treatment in Canada and does not work for everyone. If you believe medical cannabis might be right for you, please consult with your doctor.




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