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Non-contrast-enhanced magnetic resonance imaging in children with seizure disorder: pitfalls and a practical approach to use.
Non-contrast-enhanced (NCE) magnetic resonance imaging (MRI) is widely used in pediatric epilepsies. The purpose of this study was to describe the role of NCE MRI in a group of children with seizure disorder and to discuss its utility in daily practice. We systematically included all consecutive children aged 0 to 18 years, who presented to our epilepsy centre between January 2012 and March 2015 and had a NCE MRI as part of their work-up (N = 115). We collected demographic data and other laboratory results; the primary diagnosis was based on EEG and clinical data, not on MRI. https://shariki.me/ Three experts evaluated the images using specific criteria. The most frequent abnormalities were structural (93/115; 80%) including periventricular nodular heterotopia (PNH, 39/113; 35%) and focal cortical dysplasias (FCD, 19/113; 17%), and vascular (30/113; 26%) and epileptogenic (24/113; 21%) abnormalities. Aetiology was identified in 21 patients (18%). Seizure types were analysed according to the diagnostic category: for 31 (67%) of the 49 idiopathic cases, NCE MRI had no impact on the final diagnosis, but there was false-positive diagnosis in four cases. In 31 (59%) of the 54 partial epilepsy cases, NCE MRI was misleading; in the other cases, there was false-negative diagnosis in one case. These results show the utility of NCE MRI when conventional MRI is contraindicated or unsuccessful. However, the high-frequency of anomalies also illustrates that NCE MRI cannot replace MRI.Her husband John Stamos was the first to confirm the birth of their second child while walking the red carpet at the Emmy’s for his role as Coach on the TV show ‘Full House’. “Alison [Stamos] has an incredibly special, big news announcement to share this morning!“ John wrote on his Facebook page on Friday.

“They’re doing great.”

John and Alison first met during high school in a theatre class, but soon began dating.

The couple married in 1991 and Alison’s daughter Harper Grace was born in 1992.

“We’re just so thankful to be parents,” he wrote.
Read More: https://shariki.me/
     
 
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