Notes

Advantages Of Solid Phase Extraction


The process of pretreatment for what project is appropriate for SPE solid-phase extraction technology, that is, SPE solid-phase extraction is superior to conventional solvent extraction. All of these are common scenarios.

1. Treatment of organics present in water via extraction in the solid phase

Such conventional treatment is basically shaking extraction with a water-immiscible organic solvent. SPE solid phase extraction has the following advantages:

It is possible to repeat the pretreatment process quantitatively.

The process of oscillation in solvents is usually used to regulate the duration, but it is not able to regulate the frequency of oscillation, intensity, and action. Every person's oscillation patterns are different so it is hard to guarantee a consistent process for everyone. Solution extraction cannot be repeated because it is not quantifiable. When using SPE for solid phase extraction, it is easier to maintain the uniformity and stability of the column and the elution speed. The process of solid phase extraction can be repeated and measured.

Processing on-site

There's a long-standing issue in the study of organic matter within water. Organic matter can be relatively stable in ponds, reservoirs, and other types of environments however, once it is introduced to the tiny environment of the sampling bottle it's going to change drastically. Thus, many organic matter analysis techniques of water require immediate analysis that should not last more than 4 hours or less. In general, the time from returning the water to the laboratory can be longer than four hours, the sample may have changed and the accuracy of the analysis results is a possibility.

If the SPE solid-phase extraction technique is implemented because of its easy equipment, compact size and simple portability, it's feasible to conduct pretreatment when taking samples on the spot. The sampler brought back to the lab a solid-phase extraction cartridge, not a water sample. This ensures that we only work with water samples that are truly stable in composition. In terms of practical application there is a lot of work to be done to replace traditional extraction using liquid-liquid with solid-phase technology for water detection. In the present, it is not able to be completely replaced, but its development prospect is worthwhile to be looking forward to.

The reduction in organic reagents used for the process.

If water samples are processed with solid-phase extraction, organic solvents have to be used for elution. This is over tenfold less than traditional liquid/liquid extraction. QuEChERS is important for both the safety of the environment as well as the security of the researcher.

Extraction of solid-phase biomaterials from bulk biomaterials of pharmaceutical ingredients

This is a great illustration of SPE that can be used in practical applications. It is primarily used to describe the pretreatment of blood and urine samples from hospitals. The benefit of SPE in solid phase solid-phase extract is that the drug components are absorbed. This makes it suitable for batch purification.

3. Solid phase extraction of Immunoaffinity

The optimal extraction state is a specific enrichment or specific exclusion. However regardless of whether it's solution extraction or solid phase extraction they're almost identical and compatible. It is only able to extract at the "certain type" level but not at "a particular type". A" degree of extraction. The solid-phase extraction column can be utilized for the immunoaffinity method. It can also be employed to get a result that is close to theoretical extraction. The issue is that, even though the idea is good, there are fewer applications available due to the rather difficult technical requirements.
Website: https://www.quora.com/What-do-we-mean-by-liquid-liquid-extraction