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Myelodysplastic Syndrome Caused by Railroad

The bone marrow produces blood cells which mature as we age in healthy individuals. This includes red blood cells that transport oxygen, white blood cells that fight off infections and platelets that aid in the formation of blood clots and stop excessive bleeding.

Myelodysplastic Disorder is characterized by the dying of these cells in the bone marrow shortly after they enter the bloodstream. The disorder can cause fatigue, bruising, and bleeding, and can cause pinpoint spots on the skin referred to as petechiae.

Benzene Exhaust Fumes

Benzene has been proven to be a carcinogen. It has been linked with several kinds of cancers including Acute Myeloid leukemia (AML) and Myelodysplastic Disorder (MDS). People who work in fields that are exposed to harmful fumes like Benzene diesel exhaust could be at risk for developing these diseases. Railway workers are frequently exposed to this substance while working in and around rail yards.

Benzene has been identified to be a major cause of many different illnesses such as colon, bladder, kidney, esophageal, and lung cancers; blood cancers such as lymphoma, multiple myeloma and leukemia bone cancers like mesothelioma, and other health conditions like fibromyalgia anemia, and non-Hodgkin's lymphoma. Benzene exposure at work is particularly risky since it can trigger serious medical ailments.

Many of the people who lived at or were employed at Camp Lejeune from 1953 to 1987 were exposed to benzene-contaminated water. A new law allows those affected to pursue civil lawsuits seeking financial compensation for their suffering. Those who win their lawsuits will be entitled to reimbursement for all medical bills they've received as well as lost earnings due to the inability to receive treatment. They can also seek reimbursement for any future costs that might be necessary to provide their medical care.

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Agricultural chemicals used to kill weeds as well as control pests have been shown to increase the risk for myelodysplastic syndrome. These chemicals can cause asthma, cancer and birth defects for unborn babies.

According to research, people who have been exposed to glyphosate (an herbicide widely used in California's Salinas Valley) are at a higher risk of developing myelodysplastic disorder later in life. This chemical is also associated with liver inflammation and metabolic disorders.

Other exposures that can increase the risk of developing myelodysplastic syndrome include long-term or chronic exposure to benzene, rubber-based chemical compounds such as diesel exhaust fumes and radiation. Rubber workers and wood product workers are at a higher risk of developing myelodysplastic Syndrome.

Many railroad workers are exposed to benzene through the use solvents and degreasers. Solvents such as perchloroethylene and trichloroethylene are frequently employed in railway shops to clean metal parts as well as other industrial equipment. Railroad car department employees as well as hostlers who refill trains are frequently exposed to these chemicals, as well. These solvents for railroads could be contaminated with dangerous substances, such as ammonia which can increase the risk of developing myelodysplastic syndrome.

Toxic Chemicals

Railroad workers are exposed to toxic chemicals and dangerous chemicals, like TCE which has been associated to myelodysplastic conditions that develop into acute myeloid lymphoma. TCE is a solvent used for cleaning equipment and degreasing metals. It is a carcinogen that can be inhaled and ingested. The EPA has classified TCE as a chemical that could pose health risks. It must be handled safely, stored and utilized in a manner that is safe.

In healthy individuals, bone marrow creates immature blood cells that grow and mature in the bloodstream over time. In patients with myelodysplastic conditions the cells are not normal, and they are unable to mature properly. This causes a decline of healthy red blood cells, white blood cells and platelets. The symptoms include fatigue, infections caused by too few white blood cells and bleeding caused by a shortage of platelets.

The World Health Organization divides myelodysplastic disorders into subtypes depending on the type(s) of blood cells that are affected. Patients with myelodysplastic syndromes with single-lineage dysplasia have less than the normal white blood cells. However, those with multilineage dysplasia are affected by two or more types of abnormal blood cells. A rare type of myelodysplastic disease is characterized by sideroblasts in which the existing red blood cells are surrounded by rings of iron that are overflowing.

In addition, to the medical expenses suffered by victims, their families deserve compensation for the loss of income resulting from not working during treatment. Victims also need compensation for the emotional trauma they have suffered.

Genetic Testing

Genetic testing can find changes (mutations) in your DNA that increase your chances of getting a specific genetic disorder. These tests can analyze just one gene, a group of genes, or all your DNA. Genomic tests are genetic tests that test your entire DNA.

Chromosomes are long strings of genes. Some tests examine changes in chromosomes, instead of changes in genes, such as karyotype and chromosomal microarrays.

Some genetic tests can determine whether you are suffering from a genetic mutation which increases your risk of developing a disease before any symptoms appear. These predisposition or predictive tests will help your doctor decide whether you should take preventative measures to prevent the development of a disease or to plan for early treatment if it occurs.


A New Orleans-based company and its principals have agreed to pay $42.6M to settle claims that they benefited from kickbacks to send unnecessary pharmacogenetic tests to Medicare. The company and its three principals signed a deal to a 25-year suspension from participating in federal healthcare programs. The lawsuit was filed by former LabCorp employee Donna Hecker-Gross, on behalf of the United States under the False Claims Act.

Read More: https://sites.google.com/view/railroadcancersettlements