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oral dosage highly individualized based on control of abstine symptoms without respiratory depression or marked sedation, if patient can't tolerate oral, give I.M. or subcutaneously [ usually at about 25% of total daily P.O dosage] in two injections.
For chronic pain, 2;5 to 10 my P.O.I.M or subeutaneouelly q 3 to 4 hours as needed; abjust dosage and dosing interval as needed. For severe Chronic pain [ as in terminal illness] 5 to 20 my P.O. q 6 to 8 hours
respiratory; depressed cough reflex, hypouentilation, wheezing, asthma exacerbation, atelectasis, pulmonary edema, bronchospasm, respiratory depression or, apnea.
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united Kingdom of Great Britain and Northern lreland [note- Great Britain includes England schotland, and wales]
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