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The synthetic drug 3,4-methylenedioxy-methamphetamine (MDMA) alters mood and perception (awareness of surrounding objects and conditions). The chemical composition of MDMA is comparable to that of hallucinogens and stimulants and produces feelings of increased energy, pleasure, emotional warmth, as well as distortions in time and sensory perception.



MDMA was first popular in nightclubs and all-night dance parties ("raves"), but it now affects a wider range of people who use the term Ecstasy or Molly.



What are the methods used by people to utilize MDMA?



MDMA is typically taken in capsules or tablets. However, some people take the liquid or powder form. Molly is shorthand for "molecular" and refers to the "pure" MDMA powder. The majority of capsules are sold. However, those who purchase Molly powder (or capsules) often receive other drugs like synthetic cathinones ("bath sals") in lieu (see page 3 "Added Risk of MDMA".



Certain people mix MDMA with other drugs such as alcohol or marijuana.



What are the effects of MDMA on the brain?



MDMA stimulates three brain chemical pathways



Dopamine is a stimulant that increases energy and activity, and functions in reward system to reinforce behavior.



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MDMA * Page 2 * June 2020



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* Norepinephrine--increases heart rate and blood pressure, which is especially dangerous for people who have heart or blood vessel problems.



Serotonin regulates mood as well as appetite and other bodily functions. It also stimulates hormones that influence sexual arousal as well as trust. MDMA users report feeling closer to their loved ones, elevated moods, and a sense of empathy.



Other side effects include nausea and blurred vision.



MDMA effects last between 3 and 6 hours. But, many take another dose when the effects from the first one start to diminish.



In the weeks after moderate use of a drug, a person may experience: * irritability • impulsiveness and aggression depression



* Sleep issues



* stress



* Memory and attention issues * less appetite * less interest in and enjoyment from sexual sex



MDMA and marijuana may partially be the reason for these effects.








Is MDMA habit-forming?



The research on whether MDMA is addictive differs. Experiments on MDMA addiction have shown that MDMA is a self-administration drug for animals. This is a significant indicator of abuse potential for a drug, but it's not as significant as the effect of cocaine.



There are people who experience withdrawal symptoms, which are signs of addiction.



* Exhaustion * Loss of appetite * Depression * Having difficulty concentrating








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