Notes

Perfusion
In physiology , perfusion (from the Latin " perfundere ", to pour over, to sprinkle) or tissue perfusion is the process that supplies an organ with the nutrients and oxygen necessary for its metabolism , its healthy biochemical activity within the organism.

In an animal equipped with a blood system , this supply is carried out by the blood which circulates from the arteries towards the capillary vessels which irrigate the biological tissues . Perfusion can then be measured by the flow of blood that irrigates the organ in question.

After surgical removal , an organ can be placed under artificial perfusion so as to keep it alive , for example while waiting to be transplanted .

Acceptances
In extenso , in the context of medical treatment , the term infusion can also refer as a whole to a drip system allowing the parenteral administration of drugs by infusion . When this system is connected to a peripheral or deep venous line (central venous line ), it is called an intravenous infusion . It can also also be a subcutaneous device, this is called the technique of hypodermoclysis , or more simply, subcutaneous infusion .
Hypo- and hyper-perfusion
We speak of hypoperfusion when the level of perfusion of an organ is below a reference value, for example below the need necessary for the proper functioning of the organ. Similarly, Perfusion Rate Calculator refers to stronger than normal perfusion.

These alterations in perfusion may be the consequence of circulatory abnormalities. For example, hypoperfusion can result from ischemia or a drop in blood pressure which, when affecting the brain , can lead to syncope . Hypoperfusion can also be the cause of pathological situations: fetal renal hypoperfusion, for example, which can be due to the taking of NSAIDs by the pregnant woman, causes oligohydramnios , harmful for the correct development of the fetus.

But hyperperfusion does not necessarily reflect a pathological mechanism . For example, in the brain , when a brain area is recruited to perform an operation (such as when the auditory cortex is activated when a sound is heard ), cerebral blood flow temporarily increases in that region; this is the hemodynamic response . The measurement of this local hyperperfusion is the basis of various cerebral imaging techniques .

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