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Common side effects :
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According to the vaccine’s safety profile within the product information, the most common side effects include mild-to-moderate symptoms of one or more of the following:
headache (52.6%)
fatigue (53.1%)
muscle or joint pain (44% or 26.4%)
fever (33.6%)
chills (31.9%)
nausea (21.9%)
The percentages are based on reports from four clinical trials with a total of 23,745 participants.Individuals also commonly reported pain and irritation at the site of the vaccine injection.Additionally, an allergic reaction to certain ingredients in the vaccine may occur. Symptoms of an allergic reaction may include hives, a rash, swelling, and respiratory symptoms.There have also been a few cases of anaphylaxis, which refers to a severe and potentially life threatening allergic reaction. However, anaphylaxis is a very rare event.According to the Medicines & Healthcare products Regulatory Agency (MHRA), out of 19.5 million administered doses of Vaxzevria, only 455 (0.002%) were associated with an anaphylaxis-related adverse reaction.People who have known allergies to any of the ingredients — the active substance itself or any ingredients listed under the product information’s “List of excipients” — are advised against receiving the vaccine.All the side effects listed above are similar to those associated with other vaccines, as the Centers for Disease Control and Prevention (CDC)Trusted Source indicate for the Pfizer-BioNTech and Moderna vaccines.
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