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Deriton, protein gibi büyük moleküGlu maddelere kargı yarn geçirgen, elektrolit, üre ve gls bi kücük moleküllü maddelere karşı ise tam geçirgendir. Bu nedenle periton zarnın iki rafindaki moleküller, her iki yönde hareket edebilirler. Periton diyalizi tedavisinde periton bogluğu, periton zari ve diyaliz solüsyonları kullanılır. Periton diyalizinin temel ilkesi, periton bodluğundaki sıvı ile kan arasındaki yoğunluk farkına bağlı olarak, kanda bulunan ve diyaliz SAVISinda bulunmayan, vücuttan atılması gereken maddelerin (sıVI ve elektrolitleri) diyaliz sıVI- sma geçmesidir. Diffüzyon ve ozmos ile peritonun her iki yanındaki madde konsantrasyonlan OSnda bir denge kurulur. Üremik toksik maddelerin kandaki yoğunlukları azalıp diyaliz sıvi- Sndaki yoğunluğu arttıkça, moleküllerin geçişi azalır ve sonuçta peritonun her iki yanındaki rigunluklar aynı olduğunda molekül geçişi durur.

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