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General Adaption Syndrome is a response your body has to stress and it comes in three stages. The three stages are alarm reaction, resistance, and exhaustion how these stages work is alarm reaction is when you get a distress signal to a part of your brain called the hypothalamus. It's the part of the brain that creates a trigger hormone that helps releases the hormone known as stress, it increases your heart rate and BP levels. Resistance is the part of the stage where the body tries to fight off the changes occurring after the stress from the first stage started, it tries to calm down the body and returns it to the normal state. Then the final stage exhaustion at this point the body is unable to fight off stress and is now subject to endure anxiety, depression and of course tiredness.

SAM system plays a role in all this because this triggers the adrenaline there for also triggers your fight or flight response. It also works up your nerves such as making your palms sweaty and making your heart beat faster. Once this is over it is done it has no more effects on the body. Then the HPA axis is activated by the stress that occurs within the first stage. It is what sends the signals around the body that helps the person deal with the stress. So this part would really help out in the resistance/exhaustion stages. This is how they are helpful to GAS.
     
 
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