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PQQ:Pyrroloquinoline quinone:NMN:Nicotinamide Mononucleotide:Phosphatidylserine:Anti-aging supplements
Pyrroloquinoline quinone
Nicotinamide is a B vitamin, also known as nicotinamide, which is the form of nicotinamide. In recent years, the whitening effect of nicotinamide has attracted much attention, and nicotinamide cosmetics have become the "pet" of the market. However, not everyone is suitable for ceramide cosmetics, so please pay attention to the dosage.
Nicotinamide has various effects
Nicotinamide has various effects. It is commonly used in whitening and freckle removing, anti wrinkle and moisturizing cosmetics. It also has application prospects in the treatment of skin diseases such as allergic dermatitis and acne.
Nicotinamide can reduce skin pigmentation. Nicotinamide plays a role in melanin deposition, avoiding melanin deposition from melanocytes to keratinocytes. Research shows that nicotinamide can effectively reduce melanin precipitation, promote dirt dilution and improve skin condition. In a randomized double-blind study, researchers found that nicotinamide can reduce facial pigmentation.
At the same time, nicotinamide can promote the metabolism of skin cells, promote the synthesis of collagen, improve cell activity function, promote the metabolism of keratinocytes containing melanin and reduce the deposition of melanin in the epidermis.
In addition, nicotinamide can also promote the synthesis of epicortisone, improve skin resistance, improve skin texture and supplement skin moisture. Topical nicotinamide can reduce transcutaneous water loss, reduce sebum secretion and improve skin barrier function. It can improve the tightness of stratum corneum, increase the thickness of stratum corneum, improve the maturity of stratum corneum, and improve the function of moisturizing and skin barrier.
Nicotinamide is an antioxidant, which can prevent the damage of cells and cell membrane to free radicals, remove superoxide anion free radicals acting on inflammation, and has local anti-inflammatory effect.
Beware of side effects such as allergy
Most studies show that using nicotinamide cosmetics is safe, but some consumers will have skin redness, allergy and itching after use. In the comparative experiment of nicotinamide gel and clindamycin gel, some of the subjects who used nicotinamide gel had mild side effects such as itching, burns and so on. In order to avoid this situation, it is recommended that consumers conduct tests on the inside of their arms and behind their ears before using nicotinamide cosmetics to avoid redness and tingling on their faces.
The concentration of nicotinamide in skin care products has an important impact on product safety. Nicotinamide cosmetics have high safety for long-term use, but the daily dosage shall not exceed 3 grams. The results show that when the concentration of nicotinamide in cosmetics exceeds 4%, 20% of people will have intolerance. Therefore, people who are sensitive to skin and patients with dermatitis must carefully use high concentration nicotinamide products.
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