Notes

Difference in the Ability of Compactin and Oxidized

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<img class=" <a href=" https: squareblogs.net vaultdream5 oxidized-cholesterol-and-vegetable-oils-identified-as-the-main">This Author ="max-height:300px;max-width:400px;" itemprop="image" src="https://www.pnas.org/content/106/44/18563/F1.large.jpg" alt="Content of Oxidized Cholesterol Derivatives in Copper-Oxidized LDL a - Download Table"/&gt;<span style="display:none" itemprop="caption">Oxidized Cholesterol in the Diet Accelerates the Development of Aortic Atherosclerosis in Cholesterol-Fed Rabbits - Arteriosclerosis, Thrombosis, and Vascular Biology</span>
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<h1 style="clear:both" id="content-section-0">What Does Oxidized cholesterol species as signaling molecules in the Do?<br></h1>
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<img width="310" src="https://www.liverphil.org/wp-content/uploads/2020/12/Screenshot-2020-12-08-at-3.08.59-PM.png">
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<p class="p__0">The objective of the present research study was to identify whether oxidized cholesterol in the diet plan accelerates atherosclerosis in low density lipoprotein receptor- (LDLR) and apolipoprotein E- (apo E) deficient mice. Mice were fed either a control diet plan or a diet plan consisting of oxidized cholesterol. For LDLR-deficient mice, the control diet plan consisted of regular mouse chow to which 1. 0% cholesterol was included. The oxidized diet was similar to the control diet plan other than that 5% of the included cholesterol was oxidized. In apo E-deficient mice, the control diet consisted of 0. 15% cholesterol, whereas in the oxidized diet, 5% of the added cholesterol was oxidized.</p>
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<img class="featurable" style="max-height:300px;max-width:400px;" itemprop="image" src="https://www.researchgate.net/profile/Hossam-El-Beltagi/publication/236945774/figure/fig1/AS:299505510567940@1448419086980/Major-pathways-of-cholesterol-oxidation-ing-them-into-most-toxic-triols-The-side-chain_Q320.jpg" alt="Oxidized Cholesterol Strategy Review: Let's Explore The Guide's Contents!"><span style="display:none" itemprop="caption">Structures of cholesterol and its oxidized metabolites examined in this - Download Scientific Diagram</span>
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<p class="p__1">In mice fed the oxidized-cholesterol diet plans, the levels of oxidized cholesterol in sera were increased. At the end of the experiment, aortas were gotten rid of and atherosclerosis was evaluated. We discovered that in LDLR-deficient mice, feeding of an oxidized-cholesterol diet plan resulted in a 32% boost in fatty streak lesions (15. 93+/ -1. 59% versus 21. 00+/ -1. 38%, P.</p>
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