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Another way, maybe culture cells which grows into tissue then implant to the targeted area - the implanted tissue is compatible with the heart tissue and can the grow together to close the hole. The tissue is injectable through a small needed, but can unfold after it is released
Sometimes the implant can be made from a special designed biocompatible biomaterials, for example polymer. It can have the same function as heart tissue. The polymer can contain either tissue cells and or drugs. the polymer has specific characteristics, that can release gradually the drug or degrade so to release tissues to targeted area. The implant can either have therapeutic effects or act as tissue itself or both
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